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Malignant Mesothelioma Treatment

General Information About Malignant Mesothelioma

KEY POINTS

  • 1. Malignant mesothelioma is a disease in which malignant (cancer) cells form in the lining of the chest or abdomen.
  • 2. Being exposed to asbestos can affect the risk of malignant mesothelioma.
  • 3. Signs and symptoms of malignant mesothelioma include shortness of breath and pain under the rib cage.
  • 4. Tests that examine the inside of the chest and abdomen are used to detect (find) and diagnose malignant mesothelioma.
  • 5. Certain factors affect prognosis (chance of recovery) and treatment options.

Malignant mesothelioma is a disease in which malignant (cancer) cells form in the lining of the chest or abdomen.

Malignant mesothelioma is a disease in which malignant (cancer) cells are found in thepleura (the thin layer of tissue that lines the chest cavity and covers the lungs) or theperitoneum (the thin layer of tissue that lines the abdomen and covers most of the organsin the abdomen). Malignant mesothelioma may also form in the heart or testicles, but this is rare.

Being exposed to asbestos can affect the risk of malignant mesothelioma.

Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn’t mean that you will not get cancer. Talk to your doctor if you think you may be at risk.
Most people with malignant mesothelioma have worked or lived in places where theyinhaled or swallowed asbestos. After being exposed to asbestos, it usually takes a long time for malignant mesothelioma to form. Living with a person who works near asbestos is also a risk factor for malignant mesothelioma.

Signs and symptoms of malignant mesothelioma include shortness of breath and pain under the rib cage.

Sometimes the cancer causes fluid to collect in the chest or in the abdomen. Signs andsymptoms may be caused by the fluid, malignant mesothelioma, or other conditions. Check with your doctor if you have any of the following:
  1. Trouble breathing.
  2. Cough.
  3. Pain under the rib cage.
  4. Pain or swelling in the abdomen.
  5. Lumps in the abdomen.
  6. Constipation.
  7. Problems with blood clots (clots form when they shouldn’t).
  8. Weight loss for no known reason.
  9. Feeling very tired.

Tests that examine the inside of the chest and abdomen are used to detect (find) and diagnose malignant mesothelioma.

Sometimes it is hard to tell the difference between malignant mesothelioma in the chest and lung cancer.
The following tests and procedures may be used to diagnose malignant mesothelioma in the chest or peritoneum:
  • Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patient’s health habits, exposure to asbestos, and past illnesses and treatments will also be taken.
  • Chest x-ray : An x-ray of the organs and bones inside the chest. An x-ray is a type of energy beam that can go through the body and onto film, making a picture of areas inside the body.
  • Chest x-ray; drawing shows the patient standing with her back to the x-ray machine. X-rays are used to take pictures of organs and bones of the chest. X-rays pass through the patient onto film.
  • CT scan (CAT scan): A procedure that makes a series of detailed pictures of the chest and abdomen, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.
  • Biopsy : The removal of cells or tissues from the pleura or peritoneum so they can be viewed under a microscope by a pathologist to check for signs of cancer.
  • Thoracoscopy : An incision (cut) is made between two ribs and a thoracoscope (a thin, tube-like instrument with a light and a lens for viewing) is inserted into the chest.
  • Thoracotomy : An incision (cut) is made between two ribs to check inside the chest for signs of disease.
  • Peritoneoscopy: An incision (cut) is made in the abdominal wall and a peritoneoscope (a thin, tube-like instrument with a light and a lens for viewing) is inserted into the abdomen.
  • Laparotomy : An incision (cut) is made in the wall of the abdomen to check the inside of the abdomen for signs of disease.
  • Open biopsy : A procedure in which an incision (cut) is made through the skin to expose and remove tissues to check for signs of disease.
  • Cytologic exam: An exam of cells under a microscope to check for anything abnormal. For mesothelioma, fluid is taken from the chest or from the abdomen. A pathologist checks the fluid for signs of cancer.
  • Immunohistochemistry : A test that uses antibodies to check for certain antigensin a sample of tissue. The antibody is usually linked to a radioactive substance or a dye that causes the tissue to light up under a microscope. This type of test may be used to tell the difference between different types of cancer.
  • Electron microscopy : A laboratory test in which cells in a sample of tissue are viewed under a high-powered microscope to look for certain changes in the cells. An electron microscope shows tiny details better than other types of microscopes.
  • Fine-needle (FNA) aspiration biopsy of the lung: The removal of tissue or fluid using a thin needle. An imaging procedure is used to locate the abnormal tissue or fluid in the lung. A small incision may be made in the skin where the biopsy needle is inserted into the abnormal tissue or fluid, and a sample is removed.
Source & Read More - Cancer.Gov